A Convergent Synthesis of AR-C123196 Utilising Reaction Between a Cyclic Carbonate and a Phenol for Aryl Alkyl Ether Formation

Autor:	Glyn L. Allsop, Andrea J. Cole, Eric Merifield, Allison J. Noble, Lindsay A. Purdie, Michael A. Pritchett, John T. Singleton, Melvyn E. Giles
Rok vydání:	2009
Předmět:	chemistry.chemical_classification Aryl Organic Chemistry Convergent synthesis Ether Medicinal chemistry Alkyl ether chemistry.chemical_compound chemistry Nucleophile Phenol Carbonate Organic chemistry Physical and Theoretical Chemistry Alkyl
Zdroj:	Organic Process Research & Development. 13:751-759
ISSN:	1520-586X 1083-6160
Popis:	The development of a convergent synthesis of AR-C123196 is reported in which the alkyl aryl ether linkage was formed by nucleophilic attack of a phenolic hydroxyl group onto a cyclic carbonate. This approach was successfully operated on a multikilogram scale.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::636bb73dd5dcd4e7d66db588a1acb9de https://doi.org/10.1021/op9000687 Zobrazit plný text záznamu