Staphylococcus aureus and Staphylococcus epidermidis Strain Diversity Underlying Pediatric Atopic Dermatitis
| Autor: | Evelyn L. Angulo, James E. Gern |
|---|---|
| Rok vydání: | 2018 |
| Předmět: |
Moderate to severe
030222 orthopedics biology business.industry Strain (biology) Multifactorial disease Atopic dermatitis medicine.disease_cause medicine.disease biology.organism_classification Marker gene Microbiology 03 medical and health sciences 0302 clinical medicine 030228 respiratory system Metagenomics Staphylococcus aureus Staphylococcus epidermidis Pediatrics Perinatology and Child Health medicine business |
| Zdroj: | Pediatrics. 142:S229-S230 |
| ISSN: | 1098-4275 0031-4005 |
| DOI: | 10.1542/peds.2018-2420ii |
| Popis: | AL Byrd, Deming, SKB Cassidy; NISC Comparative Sequencing Program. Sci Transl Med. 2017;9(397):eaal4651 Atopic dermatitis (AD) is a complex and multifactorial disease. Authors of previous studies have used traditional typing methods on cultivated isolates or have sequenced a bacterial marker gene to study the skin microbial communities of patients with AD. A shotgun metagenomic sequencing analysis provides greater resolution, elucidating multiple levels of microbial community assembly. Eleven children with moderate to severe AD and 7 healthy children were recruited to the National … |
| Databáze: | OpenAIRE |
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