ChemInform Abstract: Aroylisothiocyanates in Heterocyclic Synthesis: Synthesis of New Benzimidazole Derivatives with Anticipated Fungicidal Activity

Autor:	Galal A. M. Nawwar, Laila M. Chabaka, Mahmoud T. Omar
Rok vydání:	2010
Předmět:	chemistry.chemical_compound Benzimidazole Chemistry Hydrazine Organic chemistry General Medicine Hydrate Adduct
Zdroj:	ChemInform. 22
ISSN:	0931-7597
DOI:	10.1002/chin.199121169
Popis:	The reactions of aroylisocyanates with 2-cyanomethylbenzimidazole (1) lead to the formation of 1:1 adducts (2a,b,c) and the corresponding α-aroyl derivatives (4a,b,c). The adducts (2a,b) could be cyclized affording pyrimido [3,4-a] benzimidazole derivatives (5a-d). They also afforded (pyrazol-4-yl) benzimidazole derivatives (7a,b) when (2a,b,c) reacts with hydrazine hydrate. Derivatives (5c,7a) could be cyclized to pyrazolo [4′,5′:5,4] pyrimidobenzimidazoles (8,9).
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6350ed8e55f4a98521b4a6e7c7f126fd https://doi.org/10.1002/chin.199121169 Zobrazit plný text záznamu Plný text