Therapeutic antioxidant and anti-inflammatory effects of laser acupuncture on patients with rheumatoid arthritis
| Autor: | Noha A. Abd El-Latif, Fatma A. Ibrahim, Abdel Aziz A. Abdel Aziz, Aliaa Elgendy, Atef M. M. Attia, Azhar M. Elwan, Samir W. Aziz, Fatema T. Elgengehy |
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| Rok vydání: | 2016 |
| Předmět: |
0301 basic medicine
medicine.medical_specialty Antioxidant medicine.medical_treatment Glutathione reductase Dermatology Laser Acupuncture medicine.disease_cause Gastroenterology 03 medical and health sciences chemistry.chemical_compound 0302 clinical medicine Internal medicine medicine Acupuncture 030203 arthritis & rheumatology medicine.diagnostic_test business.industry medicine.disease Malondialdehyde 030104 developmental biology chemistry Rheumatoid arthritis Erythrocyte sedimentation rate Immunology Surgery business Oxidative stress |
| Zdroj: | Lasers in Surgery and Medicine. 48:490-497 |
| ISSN: | 0196-8092 |
| DOI: | 10.1002/lsm.22487 |
| Popis: | Background and Objective The laser acupuncture has many potential therapeutic effects. Currently, they are not evaluated for their therapeutic effects on rheumatoid arthritis (RA) patients. The aim of this study was to investigate the effects of laser acupuncture on the oxidative and antioxidative markers, as well as the inflammatory markers and disease activity of RA patients. Design/Materials and Methods The study was conducted on 30 RA patients and 20 healthy subjects. The patients were subjected to laser acupuncture (904 nm, 100 mW power output, 1 minute irradiation time, beam area of 1 cm2, total energy per point 6 J, energy density 6 J/ cm2, irradiance 0.1 W/cm2, frequency 10000 Hz, duty-cycle 100%) for 3 days/week for duration of 4 weeks. The acupuncture points of exposure were LI4, TE5, LI 11, DU 14, LIV3, SP6, GB34, and S36. The levels of oxidative and antioxidant markers were determined by spectrophotometric methods whereas the inflammatory markers were determined by ELISA methods. Lastly, using DAS28 scores the disease activity was assessed. Results After laser acupuncture, the study group revealed significantly increased plasma superoxide dismutase (SOD), glutathione reductase (GR), catalase activities, blood glutathione (GSH), and plasma ATP concentrations, compared to those before treatment (P |
| Databáze: | OpenAIRE |
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