ChemInform Abstract: Synthesis of 2-C- and 3-C-Aryl Pyranosides

Autor:	J. Cleophax, Isabelle Hladezuk, Gabor Lukacs, Alain Olesker
Rok vydání:	2010
Předmět:	chemistry.chemical_compound Anomer chemistry Group (periodic table) Aryl Substituent Epoxide chemistry.chemical_element Lithium General Medicine Carbohydrate Medicinal chemistry
Zdroj:	ChemInform. 29
ISSN:	1522-2667 0931-7597
Popis:	Lithium diphenylcuprate treatment of methyl 2,3-anhydro-4,6-O-benzylidene-D-pyranosides in which the anomeric substituent and the three-membered rings are cis oriented furnished the expected trans-diaxial opening products. When the relationship between the anomeric group and the epoxide was trans, the same experimental conditions led only to recovered starting material. Cyano cuprates of the type R2CuCNLi2 added stereoselectively to carbohydrate ketones at C-2 and C-3 from the opposite side relative to the anomeric substituent.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6321f72598f037c5fb4bf10d421128b2 https://doi.org/10.1002/chin.199852254 Zobrazit plný text záznamu Plný text