Antibacterial activity of Sentul fruit peel extract (Sandoricum koetjape) against Streptococcus mutans and Staphylococcus aureus

Autor: I Nyoman Wirata, null Anak Agung Gede Agung, null Ni Wayan Arini, null Regina Tedja Sulaksana, null Mochammad Choirul Hadi, null I Gusti Ayu Raiyanti
Rok vydání: 2022
Předmět:
Zdroj: Bali Medical Journal. 11:1533-1536
ISSN: 2302-2914
2089-1180
DOI: 10.15562/bmj.v11i3.3666
Popis: Introduction: Infectious mouth diseases are caused by microorganisms such as Staphylococcus aureus and Streptococcus mutans. Sentul fruit peel extract contains several phytochemical compounds, flavonoid compounds, saponins and tannins are aromatic hydroxyl groups that act as antibacterial so that they can be used as a treatment for infections of the mouth. This study aimed to determine the inhibitory ability of Sentul fruit peel extract (Sandoricum koetjape) against Streptococcus mutans and Staphylococcus Aureus bacteria which can cause oral infections. Method: Sentul fruit peel simplicia was extracted by maceration method with ethanol for 24 hours. The maceration method was chosen in this study because it is a method that is easy to do and uses simple tools, which is enough to soak the sample in a solvent. A filtering process followed this and the filtrate was then evaporated with a vacuum rotary evaporator at a temperature of 45oC, so that a thick extract was produced. The maceration process was repeated 2 times. After the extraction process, then proceed with liquid-liquid fractionation using distilled water. The thick extract was put into a separating funnel and distilled water was added. Then it was shaken and the aquadest fraction was taken, followed by evaporation with a vacuum rotary evaporator at 45oC, so that the aqua fraction of the ethanol extract was produced. Result: The results showed that the Sentul fruit peel extract was able to inhibit the growth of S. mutans and S. aureus bacteria as seen from the formation of a clear zone. Based on the ANOVA test, the extract concentration treatment had a significant effect (p
Databáze: OpenAIRE
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