ChemInform Abstract: Use of Rhodium Complexes with Amphiphilic and Nonamphiphilic Ligands for the Preparation of Chiral α-Aminophosphonic Acid Esters by Hydrogenation in Micellar Media

Autor:	Silke Ziegler, Christine Fischer, Ute Schmidt, Guenther Oehme, Ingrid Grassert
Rok vydání:	2010
Předmět:	Chemistry Amphiphile Hydrogenation reaction Asymmetric hydrogenation Organic chemistry chemistry.chemical_element General Medicine Enantiomer Micelle Chiral induction Rhodium Catalysis
Zdroj:	ChemInform. 30
ISSN:	1522-2667 0931-7597
Popis:	Several kinds of micelle forming amphiphiles were tested in the asymmetric hydrogenation of the prochiral dialkyl 1-benzamido-2-phenyl-ethenephosphonates in aqueous media. The chiral catalytic system [Rh(cod) 2 ]BF 4 /BPPM or amphiphilized PPM proved to be suitable for the hydrogenation reaction affording enantiomeric excesses up to 99%. A chiral induction is possible to a certain extent (up to 11% ee ) by selected chiral amphiphiles in the presence of achiral rhodium catalysts.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::62e367fb4b2a6001a66e0df97edbe3aa https://doi.org/10.1002/chin.199925025 Zobrazit plný text záznamu Plný text