TO EVALUATE THE EFFECT OF MORUS ALBA LEAVES EXTRACT ON SLEEP AND ANXIETY IN RAT MODELS

Autor:	SRIHARSHA RAYAM, KUDAGI BL, RAMYA JONNALAGADDA, RAVEENDRA KUMAR NALLABOTHULA
Rok vydání:	2021
Předmět:	Pharmacology Pharmaceutical Science Pharmacology (medical)
Zdroj:	Asian Journal of Pharmaceutical and Clinical Research. :100-102
ISSN:	2455-3891 0974-2441
DOI:	10.22159/ajpcr.2022.v15i1.43569
Popis:	Objectives: The objectives of the study were to study the effect of Morus alba leaves extract (MAE) on sleep by phenobarbitone-induced sleeping time and the antianxiety effect by elevated plus maze apparatus model in rats. Methods: In this study, the effect of MAE on sleep was evaluated by the phenobarbitone-induced sleeping time of rats. The onset and the duration of sleep were recorded in minutes. The antianxiety effect was evaluated by the elevated plus maze apparatus model in rats. During 5 min test period, the number of entries into the open arm and closed arm and time spent in the open arm and closed arm were recorded in seconds. Results: MAE at the dose 200 and 400 mg/kg, highly significantly (p
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::62d577526cf2c089581fe3c3df20d867 https://doi.org/10.22159/ajpcr.2022.v15i1.43569 Zobrazit plný text záznamu