Natural and synthetic cytomedines in nerve tissue culture
| Autor: | V. B. Okulov, N. I. Chalisova, V. Kh. Khavinson |
|---|---|
| Rok vydání: | 1998 |
| Předmět: |
chemistry.chemical_classification
medicine.medical_specialty Peptide Sensory system Embryo General Medicine Biology Neurite regeneration Embryonic stem cell General Biochemistry Genetics and Molecular Biology Tissue culture medicine.anatomical_structure Endocrinology chemistry Cortex (anatomy) Internal medicine medicine Explant culture |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 125:294-297 |
| ISSN: | 1573-8221 0007-4888 |
| Popis: | Effect of cortexin, epithalamine, and human cortical and pineal peptides on the growth of sensory neurons and the development of cortex and subcortical structures is studied in organotypic culture of chick embryo brain (embryonic days 10–11). In doses of 2–200 ng/ml these preparations exhibit stimulating effect on spinal ganglia, which is seen on day 3 in culture. Cortexin (100 ng/ml) and brain peptide (20 ng/ml) stimulate growth of cultured brain cortex explants. Epithalamine (200 ng/ml) and pineal peptide (100 ng/ml) stimulate the development of subcortical structures in culture. These peptides can be used as stimulators of neurite regeneration. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
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