Fatal hyperammonemia associated with disseminated Serratia marcescens infection in a pediatric liver transplant recipient
| Autor: | Helen M. Evans, Emma Glamuzina, Simon Chin, Emma Best, Stephen Mouat, Jonathan Bishop |
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| Rok vydání: | 2018 |
| Předmět: |
Transplantation
medicine.medical_specialty Gastrointestinal bleeding Serratia infection business.industry medicine.medical_treatment Hyperammonemia 030230 surgery Liver transplantation medicine.disease Gastroenterology Portal vein thrombosis Sepsis 03 medical and health sciences 0302 clinical medicine Biliary atresia Internal medicine Pediatrics Perinatology and Child Health medicine 030211 gastroenterology & hepatology business |
| Zdroj: | Pediatric Transplantation. 22:e13180 |
| ISSN: | 1397-3142 |
| Popis: | Hyperammonemia is a rare and important complication post-liver transplantation. We review a case of a 5-month-old boy with biliary atresia who received a split liver transplant following a variceal bleed. The transplant was complicated by recurrent portal vein thrombosis. Colonized with Serratia marcescens pretransplant, he developed disseminated infection associated with very high levels of ammonia that led to his death. It is important to be aware of serum ammonia levels in patients with portal vein thrombosis, particularly in the setting of gastrointestinal bleeding and sepsis. |
| Databáze: | OpenAIRE |
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