Association Study of Single Nucleotide Polymorphisms in KDM3A and LOC203413 Genes with Male Infertility

Autor:	Manonmani S, Poongothai J, Jeeva Se
Rok vydání:	2016
Předmět:	Infertility Genetics education.field_of_study Population Single-nucleotide polymorphism General Medicine Biology medicine.disease Male infertility Andrology Exact test Oligospermia medicine SNP Restriction fragment length polymorphism education
Zdroj:	Andrology-Open Access.
ISSN:	2167-0250
DOI:	10.4172/2472-1212.1000171
Popis:	A case-control study conducted on fertile and infertile men in Coimbatore population. The study, aimed to identify and associate the following two single nucleotide polymorphisms (SNPs) rs2030259 and rs5911500 in genes KDM3A (lysine (K)-specific demethylase 3A) and LOC203413.The SNPs were identified by restriction fragment length polymorphism (RFLP) technique in 17 normospermic individuals and in 13 infertile males (9 oligospermic and 4 azoospermic) and results were analysed using fisher’s exact test. Although the polymorphisms were found in both fertile and infertile men, no significant association is found for both 2 SNPs with infertility from the samples observed.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::62beb5b571748f8e9349b83a1431bb5c https://doi.org/10.4172/2472-1212.1000171 Zobrazit plný text záznamu