Experimental infections of baboons (Papio spp.) and vervet monkeys (Cercopithecus aethiops) with Trichinella zimbabwensis and successful treatment with ivermectin

Autor:	Edoardo Pozio, E. Matenga, Samson Mukaratirwa, B. M. Dzoma, Luciano Sacchi, S. D. Ruziwa
Rok vydání:	2008
Předmět:	General Veterinary biology Cell volume Creatinine phosphokinase Physiology General Medicine Cercopithecus aethiops Ivermectin biology.animal Edema Immunology medicine Trichinella zimbabwensis medicine.symptom Blood parameters Baboon medicine.drug
Zdroj:	Onderstepoort J Vet Res. 75
ISSN:	2219-0635 0030-2465
DOI:	10.4102/ojvr.v75i2.16
Popis:	Experimental Trichinella zimbabwensis infections were established in three baboons (Papios p.)and four vervet monkeys (Cercopithecuase thiops) and the clinical-pathological manifestations assessed. The infected animals showed clinical signs ranging from fever, diarrhoea, periorbitaol edema and muscular pain in varying degrees. One baboon became blind due to the infection. Levels of creatinine phosphokinase and lactated ehydrogenase increased to reach a peak on Day 42 post-infection(pi)for both baboons and monkeys. Blood parameters such as packed cell volume, levels of red blood cells and white blood cells did not change significantly from the normal ranges except for the levels of eosinophils which peaked above the normal ranges at Day 28 and 56 pi in baboons and at Day 56 pi in monkeys.
Databáze:	OpenAIRE
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