Cancer mortality among European asphalt workers: An international epidemiological study. I. Results of the analysis based on job titles
| Autor: | Sverre Langård, Hans Kromhout, Christoffer Johansen, Timo Partanen, Timo Kauppinen, Ingvar A. Bergdahl, Igor Burstyn, Wolfgang Ahrens, Rainer Frentzel-Beyme, Sylvie Cénée, Paolo Boffetta, Bengt Järvholm, Judith Shaham, Walter Schill, Isabelle Stücker, Pirjo Heikkilä, Britt G. Randem, Ole Svane, Gilles Ferro, Mariëtte Hooiveld, Dick Heederik |
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| Rok vydání: | 2002 |
| Předmět: |
medicine.medical_specialty
business.industry Mortality rate Public Health Environmental and Occupational Health 030210 environmental & occupational health Confidence interval 3. Good health Occupational medicine 03 medical and health sciences symbols.namesake 0302 clinical medicine Relative risk Environmental health Epidemiology Cohort medicine symbols 030212 general & internal medicine Poisson regression business Cohort study |
| Zdroj: | American Journal of Industrial Medicine. 43:18-27 |
| ISSN: | 0271-3586 |
| Popis: | Background Inhalation of bitumen fumes is potentially carcinogenic to humans. Methods We conducted a study of 29,820 male workers exposed to bitumen in road paving, asphalt mixing and roofing, 32,245 ground and building construction workers unexposed to bitumen, and 17,757 workers not classifiable as bitumen workers, from Denmark, Finland, France, Germany, Israel, the Netherlands, Norway, and Sweden, with mortality follow-up during 1953–2000. We calculated standardized mortality ratios (SMRs) and 95% confidence intervals (CIs) based on national mortality rates. Poisson regression analyses compared mortality of bitumen workers to that of building or ground construction workers. Results The overall mortality was below expectation in the total cohort (SMR 0.92, 95% CI 0.90–0.94) and in each group of workers. The SMR of lung cancer was higher among bitumen workers (1.17, 95% CI 1.04–1.30) than among workers in ground and building construction (SMR 1.01, 95% CI 0.89–1.15). In the internal comparison, the relative risk (RR) of lung cancer mortality among bitumen workers was 1.09 (95% CI 0.89–1.34). The results of cancer of the head and neck were similar to those of lung cancer, based on a smaller number of deaths. There was no suggestion of an association between employment in bitumen jobs and other cancers. Conclusions European workers employed in road paving, asphalt mixing and other jobs entailing exposure to bitumen fume might have experienced a small increase in lung cancer mortality risk, compared to workers in ground and building construction. However, exposure assessment was limited and confounding from exposure to carcinogens in other industries, tobacco smoking, and other lifestyle factors cannot be ruled out. Am. J. Ind. Med. 43:18–27, 2003. © 2003 Wiley-Liss, Inc. |
| Databáze: | OpenAIRE |
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