Crystal Structure and Properties of the Carboxylic Acid Derivatives ofSchizonpeta mulifida(L.) Briq

Autor:	Ji-Cheng Yu, Xiao-Jing Zhao, Li-Ying Zhang, Sheng-Di Fan, Hui-Ming Jiang, Ju-Tao Liu
Rok vydání:	2008
Předmět:	chemistry.chemical_classification Schizonepeta biology Silica gel Carboxylic acid Chemical shift General Chemistry Crystal structure Carbon-13 NMR biology.organism_classification chemistry.chemical_compound chemistry Proton NMR Organic chemistry Single crystal Nuclear chemistry
Zdroj:	Chinese Journal of Chemistry. 26:1129-1132
ISSN:	1614-7065 1001-604X
DOI:	10.1002/cjoc.200890201
Popis:	The chemical constituents of the carboxylic acid derivatives from the ear of Schizonepeta were investigated. 1H and 13C NMR chemical shifts of the carboxylic acid derivatives were accurately assigned. Two carboxylic acid derivative constituents were separated by a silica gel column. The structures were elucidated by the physical and chemical properties, IR, 1H NMR, 13C NMR, MALDI-TDF-MS and X-ray single crystal diffractometry. They were identified as 3-imino-N-(α-imidoethylamino)butyrolactam and neononane tetracid, respectively. The antitumoral activity on liver tumor cells SMMC-7721 was determined invitro. The experimental results showed that the former was better than the latter, and with increasing the concentration of the former the inhibitory activity was increased.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::629a56b84e9e01a37e5b08ee88764ee6 https://doi.org/10.1002/cjoc.200890201 Zobrazit plný text záznamu Plný text