Detection of the Multidrug Resistance Phenotype in Leukemic Cells with an In Vitro Chemosensitivity Assay

Autor:	Josef D. Schwarzmeier, Thomas Lion, F. Tichelmann, F. Prischl, S. Kürkciyan
Rok vydání:	1993
Předmět:	chemistry.chemical_classification Tumor cells Biology medicine.disease Resistant cell In vitro Malignant disease Leukemia chemistry Cancer research medicine Nucleotide Chemosensitivity assay Multidrug resistance phenotype
Zdroj:	Leukemias ISBN: 9783642770852
DOI:	10.1007/978-3-642-77083-8_40
Popis:	Detection of the pattern of resistance of tumor cells to chemotherapeutic agents is an important task in the treatment of patients with malignant diseases. In our laboratory, we established and optimized an in vitro chemosensitivity assay based on the incorporation of radioactively labeled nucleotides in the presence of various drugs. Using this assay, we analyzed the pattern of resistance in 62 patients with leukemia.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::62840678218630544d9d981ea408b018 https://doi.org/10.1007/978-3-642-77083-8_40 Zobrazit plný text záznamu