Therapeutic Potential of Cannabidiol (CBD) for Skin Health and Disorders
| Autor: | Kelly M. Glynn, Arun Rajgopal, Sunghan Yim, Sudhir M. Baswan, Allison E. Klosner, Kausar Malik, Nathan Stern |
|---|---|
| Rok vydání: | 2020 |
| Předmět: |
Cannabinoid receptor
biology business.industry Dermatology Bioinformatics biology.organism_classification medicine.disease Endocannabinoid system 030207 dermatology & venereal diseases 03 medical and health sciences 0302 clinical medicine 030220 oncology & carcinogenesis Psoriasis Synthetic cannabinoids medicine Dermatological disorders Cannabis business Receptor Cannabidiol medicine.drug |
| Zdroj: | Clinical, Cosmetic and Investigational Dermatology. 13:927-942 |
| ISSN: | 1178-7015 |
| Popis: | Though there is limited research confirming the purported topical benefits of cannabinoids, it is certain that cutaneous biology is modulated by the human endocannabinoid system (ECS). Receptors from the ECS have been identified in the skin and systemic abuse of synthetic cannabinoids, and their analogs, have also been associated with the manifestation of dermatological disorders, indicating the effects of the ECS on cutaneous biology. In particular, cannabidiol (CBD), a non-psychoactive compound from the cannabis plant, has garnered significant attention in recent years for its anecdotal therapeutic potential for various pathologies, including skin and cosmetic disorders. Though a body of preclinical evidence suggests topical application of CBD may be efficacious for some skin disorders, such as eczema, psoriasis, pruritis, and inflammatory conditions, confirmed clinical efficacy and elucidation of underlying molecular mechanisms have yet to be fully identified. This article provides an update on the advances in CBD research to date and the potential areas of future exploration. |
| Databáze: | OpenAIRE |
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