Su1046 Early-Onset Colorectal Cancer Is Independently Associated With Shorter Overall Survival

Autor:	Kidist K. Yimam, Edward W. Holt, Michael Abel, Christine Wong, Taehyun P. Chung, Michael S. Verhille, Richard E. Shaw, Joyce Louie
Rok vydání:	2013
Předmět:	Oncology medicine.medical_specialty Hepatology Colorectal cancer business.industry medicine.medical_treatment Osteoporosis Gastroenterology MEDLINE Cancer Bisphosphonate medicine.disease Internal medicine Epidemiology medicine Observational study business Early onset
Zdroj:	Gastroenterology. 144:S-385
ISSN:	0016-5085
DOI:	10.1016/s0016-5085(13)61414-6
Popis:	BACKGROUND: Colorectal cancer (CRC) is the third most common cancer, as well as the third most common cause of cancer deaths in the United States. Bisphosphonates are antiresorptive agents widely used in treating and preventing osteoporosis. Several large studies have recently reported a reduced risk of CRC with bisphosphonate use, however no meta-analysis on the subject exists. AIM: We aimed to conduct a meta-analysis of existing observational studies and thus provide a quantitative estimate of the association between bisphosphonate use and the risk of CRC. METHODS: We followed the Meta-Analysis of Observational Studies in Epidemiology (MOOSE) guidelines in performing our systematic review. A search was conducted through Medline, PubMed, Embase, and Current
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::627580b09d2e449965459c4f027e42ff https://doi.org/10.1016/s0016-5085(13)61414-6 Zobrazit plný text záznamu