Chronic Lymphocytic Leukemia Presenting as a Pituitary Mass Lesion
| Autor: | F Yan-Go, J S Fain, D P Becker, H V Vinters, L Petrus, A Van Herle, F Naeim |
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| Rok vydání: | 1992 |
| Předmět: |
Pituitary gland
Pathology medicine.medical_specialty medicine.diagnostic_test business.industry Chronic lymphocytic leukemia Optic chiasm General Medicine medicine.disease Lesion Leukemia medicine.anatomical_structure Neurology hemic and lymphatic diseases Biopsy Adrenal insufficiency Medicine Neurology (clinical) medicine.symptom business Bitemporal hemianopsia |
| Zdroj: | Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques. 19:239-242 |
| ISSN: | 2057-0155 0317-1671 |
| DOI: | 10.1017/s0317167100042335 |
| Popis: | We describe a unique case of chronic lymphocytic leukemia (CLL) in a patient who presented with bitemporal hemianopsia, adrenal insufficiency, and gonadotrophin deficiency. Studies revealed an enhancing intrasellar mass with suprasellar extension and displacement of the optic chiasm. Peripheral blood and cerebrospinal fluid (CSF) studies disclosed a monoclonal IgM kappa expressing B-cell CLL. Biopsy of the pituitary mass revealed dense infiltration of the pituitary gland by leukemic cells. This is, to our knowledge, the first reported case of CLL presenting as a pituitary mass lesion. |
| Databáze: | OpenAIRE |
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