Additive effects in palladium–indium mediated Barbier type allylations

Autor:	Ronald Grigg, Laura A. T. Cleghorn, Visuvanathar Sridharan, William S. MacLachlan, Ian R. Cooper
Rok vydání:	2003
Předmět:	Aryl Allene Organic Chemistry chemistry.chemical_element Biochemistry Medicinal chemistry chemistry.chemical_compound chemistry Cascade reaction Yield (chemistry) Drug Discovery Amine gas treating Bimetallic strip Indium Palladium
Zdroj:	Tetrahedron Letters. 44:7969-7973
ISSN:	0040-4039
DOI:	10.1016/j.tetlet.2003.08.103
Popis:	The effect of adding 1 equiv. of an amine or 0.2 equiv. of CuI to a Pd/In bimetallic cascade reaction is described. In the class 1 cascade reaction of aldehydes, aryl iodides and allene, generating homoallylic alcohols, the reaction time is reduced from 16 to 2 h and is accompanied by an impressive increase in yield.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::624225fef83fb9a97f142536fcd399ac https://doi.org/10.1016/j.tetlet.2003.08.103 Zobrazit plný text záznamu Full Text from ScienceDirect