| Autor: |
Yu. V. Soldatova, R. A. Kotelnikova, A. V. Zhilenkov, I. I. Faingold, P. A. Troshin, M. A. Kozlova, D. A. Areshidze, S. M. Aldoshin |
| Rok vydání: |
2019 |
| Předmět: |
|
| Zdroj: |
Доклады Академии наук. 488:338-341 |
| ISSN: |
0869-5652 |
| DOI: |
10.31857/s0869-56524883338-341 |
| Popis: |
It was shown for the first time that pentaamino acid derivative of fullerene C60 (potassium salt of fullerenylpenta-N-dihydroxytyrosine) effects on three targets of type 2 diabetes mellitus. It competitively inhibits the enzymes aldose reductase and sorbitol dehydrogenase and also exhibits antiglycation effect on bovine serum albumin. The enzymes inhibition constants were calculated. |
| Databáze: |
OpenAIRE |
| Externí odkaz: |
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