Synthesis of Dihydroindolo[2,3-c]carbazole as Potential Telomerase Inhibitor

Autor:	Yendry Carvajal-Miranda, Jesús A. Varela, Roy Pérez-Salazar
Rok vydání:	2015
Předmět:	chemistry.chemical_compound Telomerase chemistry 010405 organic chemistry Carbazole Stereochemistry Organic Chemistry Telomerase Inhibitor 010402 general chemistry 01 natural sciences 0104 chemical sciences
Zdroj:	Journal of Heterocyclic Chemistry. 53:762-766
ISSN:	0022-152X
Popis:	The dictyodendrins A-E were the first marine natural products that show inhibition of telomerase. A versatile and convergent route was described for the synthesis of derivatives of these pyrrolo[2,3-c]carbazole alkaloids as potential inhibitors of telomerase, by cyclotrimerization [2 + 2 + 2] of ruthenium-catalyzed diynamides diarylacetylenes.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::623abfede6e9bb2a06a471dc5aa587ef https://doi.org/10.1002/jhet.2333 Zobrazit plný text záznamu Plný text