Heterocycles with a bridging nitrogen atom. 19. Development of routes for the synthesis of oxazoloisoquinolinium salts based on phenacylation of α-methyl-1(3)-isoquinolones

Autor:	I. V. Dlinnykh, Victor B. Rybakov, Aleksandra A. Nevskaya, Eugene V. Babaev
Rok vydání:	2009
Předmět:	chemistry.chemical_classification Sodium Organic Chemistry chemistry.chemical_element Salt (chemistry) Alkylation Phenacyl Medicinal chemistry Ammonia chemistry.chemical_compound chemistry Nitrogen atom Morpholine Organic chemistry Derivative (chemistry)
Zdroj:	Chemistry of Heterocyclic Compounds. 45:93-104
ISSN:	1573-8353 0009-3122
DOI:	10.1007/s10593-009-0231-9
Popis:	Alkylation of 3-methyl-1-isoquinolone and 1-methyl-3-isoquinolone with phenacyl bromides proceeds regioselectively with the formation in the first case of only an N-phenacyl derivative and in the second only the O-derivative. The 5-methyl[1,3]oxazolo[3,2-a]isoquinolinium salt has been synthesized and its reactions with ammonia, morpholine, and sodium methylate have been investigated.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::62378bbcebaceeba0290326e353a8a45 https://doi.org/10.1007/s10593-009-0231-9 Zobrazit plný text záznamu Plný text ve formátu PDF