Cyclisations of alkynoic acids using copper(I) arylspiroborate complexes

Autor:	Andreas Decken, Eric G. Bowes, Graham M. Lee, Christopher M. Vogels, Stephen A. Westcott
Rok vydání:	2019
Předmět:	Steric effects 010405 organic chemistry Organic Chemistry chemistry.chemical_element 010402 general chemistry 01 natural sciences Biochemistry Copper 0104 chemical sciences 3. Good health Catalysis Metal Crystallography chemistry visual_art Drug Discovery visual_art.visual_art_medium Single crystal
Zdroj:	Tetrahedron. 75:2106-2112
ISSN:	0040-4020
DOI:	10.1016/j.tet.2019.02.028
Popis:	In this study we have studied the synthesis, characterization and catalytic activity of phosphinocopper(I) complexes [Cu(PPh3)3(NCCH3)][B(O2C6H4-4-R)2] (3a: R = H; 3b: R = Me; 3c: R = NO2) and [Cu(PPh3)3(NCCH3)][B(O2C6H3-3,5-di-tBu)2] (3d) containing weakly coordinating arylspiroborate ligands bearing various electronic and sterically defined characteristics. All new compounds have been characterized fully including single crystal X-ray diffraction studies for 3a and 3c and confirm that the arylspiroborate ligands do not coordinate to the copper atoms. Using these new metal complexes as precatalysts in the cyclisation of short chain alkynoic acids gave the corresponding exo-dig cyclic lactones exclusively.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::6224130f61f2322427529e88aa32782a https://doi.org/10.1016/j.tet.2019.02.028 Zobrazit plný text záznamu Full Text from ScienceDirect