Popis: |
Ever since the cloning of two distinct cannabinoid receptors and the discovery of lipids derived from arachidonic acid as endogenous ligands, cannabinoid pharmacology has received increased attention and yielded new insights in the understanding of the complex effects of smoking marijuana. Novel receptors offer the prospect of new therapeutics, and after decades of sparse research cannabinoid pharmacology is once again on the forefront of medical news. The use of molecular biology techniques, such as knockout mice, and the development of antagonists and agonists of the cannabinoid receptors are slowly unraveling a network of intricate physiological and neurological effects. |