The profile of erythrocyte enlargement due to imported cases of Plasmodium vivax infection: its impact to the patient and the community

Autor: Ani Oranda Panjaitan, Melsipa Siregar, Ronny Ronny, Ekarini Daroedono, Forman Erwin Siagian, Fitri Boru Naibaho, Muhammad Alfarabi, Silphia Novelyn, Sudung Nainggolan, Urip Susiantoro, Derilandry Isham
Rok vydání: 2020
Předmět:
Zdroj: International Journal Of Community Medicine And Public Health. 7:2499
ISSN: 2394-6040
2394-6032
Popis: Background: Imported cases of malarial vivax also induce erythrocyte enlargement. The size of enlargement depend on the size of the parasite inside the cells. The aim of the study was to examine 20 slides of positive malaria vivax and seek for erythrocyte infected malaria and measure the size of enlarged cells and its shape. As a comparison, a number of normal erythrocyte also evaluated for its size and shape.Methods: This simple cross sectional design of microscope based study was conducted in Parasitology lab, Faculty of Medicine, Universitas Kristen Indonesia, Jakarta-Indonesia, from January to June of 2019. All data collected and further processed using SPSS™.Results: A total number of 982 erythrocyte infected with P. vivax were examined individually. Those number consist of 243 immature trophozoite, 231 mature trophozoite, 251 micro-gametocyte, and 257 macrogametocyte. As a comparison also being examined 70 normal erythrocyte. Each erythrocyte infected with malaria vivax parasite enlarge to some extent, had irregular shape and the size varied based on the stage of the parasite inside the cells.Discussion: This enlarged erythrocyte is prone to cell sequestration and lysis, a condition that leads to anemia. Anemia affect not just the host but also the community. Proper management of malaria will reduce the burden to the community.Conclusions: Enlarged infected erythrocyte due to malaria vivax can cause anemia with effect to the host and also to the community.
Databáze: OpenAIRE
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