A Case of Aplastic Anemia Associated with Systemic Lupus Erythematosus: Successful Treatement with Cyclosporine
| Autor: | Sung-Il Kim, Bong Eun Lee, Seong Geun Lee, Mi Ra Cho, Ji Ryang Kim, Hee Yun Seol, Jeong Wook Lee, Seung-Hoon Baek, Jun Hee Lee |
|---|---|
| Rok vydání: | 2007 |
| Předmět: |
Autoimmune disease
myalgia medicine.medical_specialty Cyclophosphamide medicine.diagnostic_test business.industry medicine.disease Pancytopenia Gastroenterology Psychiatry and Mental health Neuropsychology and Physiological Psychology medicine.anatomical_structure immune system diseases hemic and lymphatic diseases Internal medicine Immunology Biopsy medicine Prednisolone Bone marrow medicine.symptom Aplastic anemia skin and connective tissue diseases business medicine.drug |
| Zdroj: | The Journal of the Korean Rheumatism Association. 14:384 |
| ISSN: | 1226-8070 |
| DOI: | 10.4078/jkra.2007.14.4.384 |
| Popis: | Systemic lupus erythematosus(SLE) is autoimmune disease in which involves systemic organs. Hematological manifestations are common in patients with SLE but aplastic anemia is very rare and, although various immunosuppressants have been tried, there is no established treatment in aplastic anemia associated with SLE. Furthermore, disease course and prognosis may be different from other aplastic anemia. A 42-year-old woman presented with fever, chilling, myalgia, general weakness, pancytopenia. Her bone marrow aspirate and biopsy revealed almost acellular bone marrow with rare foci of hematopoietic elements and she was diagnosed with SLE simultaneously. High-dose methyprednisolone, prednisolone and cyclophosphamide therapies had been unsuccessful in controlling pancytopenia. Cyclosproine was started and the aplastic anemia was responded. Now she was free of transfusion with more than 10 g/dL of hemoglobin. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|