C6–H Bond Functionalization of Indoles: A New Gate
| Autor: | Yunus Taskesenligil, Nurullah Saracoglu |
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| Rok vydání: | 2023 |
| Předmět: | |
| Zdroj: | Synthesis. |
| ISSN: | 1437-210X 0039-7881 |
| Popis: | Indoles are valuable precursors in medicinal, bioorganic, and material chemistry and particularly serve as a platform for diversity. However, the scope of the C6-functionalization of indoles was limited until recently. In this short review, we summarize developments in the C6-functionalization reactions of indoles involving transition-metal-catalyzed functionalization and Brønsted and Lewis acid catalyzed processes. The regioselectivity is controlled by remote-C–H activation and hydrogen bond formation.1 Introduction2 Transition-Metal-Catalyzed Functionalization3 Acid-Catalyzed Processes4 Conclusion |
| Databáze: | OpenAIRE |
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