Synthesis, characterization, and antibacterial activities of Cr(III), Co(III), Ni(II), and Mn(III) complexes of heptadentate Schiff base ligand derived from tris(2-aminoethyl)amine

Autor:	S. J. Matin, R. Ranjineh Khojasteh
Rok vydání:	2015
Předmět:	Tris Schiff base Ligand Tris(2-aminoethyl)amine General Chemistry medicine.disease_cause Medicinal chemistry chemistry.chemical_compound chemistry Salicylaldehyde medicine Organic chemistry Amine gas treating Antibacterial activity Escherichia coli
Zdroj:	Russian Journal of General Chemistry. 85:1763-1767
ISSN:	1608-3350 1070-3632
DOI:	10.1134/s1070363215070312
Popis:	This is the first study of the antibacterial activity of heptadentate Schiff base ligand (trensal) and its Cr(III), Co(III), Ni(II), and Mn(III) complexes that have been synthesized from the heptadentate Schiff base ligand derived from salicylaldehyde and tris(2-aminoethyl)amine. Heptadentate Schiff base ligand and its complexes were characterized by elemental analysis, 1H and 13C NMR, IR, and UV-Vis spectroscopy. The products were tested in vitro against the bacterial species, Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa, and Bacillus cereus by disc diffusion and micro-broth dilution methods. All compounds demonstrated potent antibacterial activity higher than the Schiff base ligand. Staphylococcus aureus was the most susceptible bacterial species to Co(III) complex while Escherichia coli and Pseudomonas aeruginosa required a relatively higher minimum inhibition concentrations of Cr(III) and Ni(II) complexes. Co(III) complex was the most potent inhibitor against Pseudomonas aeruginosa. Mn(III) complex was active against Pseudomonas aeruginosa.
Databáze:	OpenAIRE
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