Probiotics and its Effect on Slow Colonic Transit

Autor: Charlotte Nexmann Larsen, Siegbert Philipp, Arthur Ouweh, Sofia Forssten
Rok vydání: 2014
Předmět:
Zdroj: Journal of Food & Nutritional Disorders.
ISSN: 2324-9323
Popis: Slow colonic transit is a common disorder that is a contributing factor to various diseases. Most notably, it is associated with constipation and thereby affects quality of life. Various physiological factors affect colonic transit and may be influenced by microbes in general and probiotics in particular. Probiotics can be delivered in various formats with; mainly as fermented dairy products or as supplements; each with their own specific technological challenges. Probiotics have been tested in various formats for their ability to improve slow colonic transit. A search of the literature yielded 13 reports on the effects of probiotics on either colonic or oroanal transit. The quality of the studies is variable and several are uncontrolled. Although most studies indicated a reduced transit time for the probiotics group; not all did so. Notwithstanding the fact that a wide range in the doses tested, no relation between dose and effect size could be observed. From a regulatory perspective, only in Switzerland a claim for probiotics on reducing long intestinal transit has currently been approved.
Databáze: OpenAIRE