Helicobacter pylori-negative Differentiated Adenocarcinoma of the Stomach
| Autor: | Etsuo Hara, Yasuhide Ochi, Norikazu Arakura, Ayako Seki, Kenichi Suzawa, Osamu Hasebe, Toshiaki Otsuki, Manabu Takata, Yugo Iwaya, Eiji Tanaka, Tadanobu Nagaya, Mai Iwaya, Naoki Tanaka, Toshiharu Tatai, Noriko Hosaka, Tetsuya Ito, Yoko Jimbo |
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| Rok vydání: | 2015 |
| Předmět: |
Pathology
medicine.medical_specialty biology business.industry Stomach General Medicine Mucin 2 Helicobacter pylori medicine.disease biology.organism_classification digestive system diseases Early Gastric Cancer medicine.anatomical_structure Submucosa Tubular Adenocarcinoma Internal Medicine medicine Gastric mucosa Adenocarcinoma business |
| Zdroj: | Internal Medicine. 54:2857-2862 |
| ISSN: | 1349-7235 0918-2918 |
| Popis: | A 58-year-old Japanese man was diagnosed with differentiated adenocarcinoma of the stomach. Histological findings of the resected specimen revealed well- to moderately-differentiated tubular adenocarcinoma (tub1, tub2), 13 mm in diameter, which invaded into the submucosa (SM1, 300 μm) and lymphovascular lumen (ly1). Serum antibody against Helicobacter pylori (Hp) and the (13)C-urea breath test were negative, and there were no atrophic changes in the tumor-adjacent mucosa. The immunohistochemical analysis showed that gastric mucin (MUC5AC) was strongly positive and intestinal mucin (MUC2) was weakly and partially positive. According to these results, the final diagnosis of Hp-negative well-differentiated early gastric cancer was made. |
| Databáze: | OpenAIRE |
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