Popis: |
Magnetic resonance (MR) imaging is the reference modality for brain tumor diagnosis, staging, and prognosis evaluation. Identifying tumor persistence and recurrence after surgery is still one of the open issues for the multidisciplinary teams managing these patients, including neurosurgeons, radiologists, pathologists, and oncologists. Several studies have evaluated the effectiveness of conventional MR examinations for brain tumor grading and follow-up. Nevertheless, the conventional approach mainly relies on morphological evidences (lesion, edema, and necrosis volumes) and on the disruption of the blood-brain barrier as evaluated by the relative enhancement after the administration of Gadolinium (Gd)-based contrast agents. |