ChemInform Abstract: SYNTHESIS OF NEW WATER-SOLUBLE DIHYDROPYRIDINE VASODILATORS
Autor: | Ryutaro Kawai, Toichi Takenaka, Fujimoto Masaharu, Tamazawa Kazuharu, Kozo Takahashi, Murakami Masuo, Iwanami Masaru, Tadao Shibanuma |
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Rok vydání: | 1979 |
Předmět: | |
Zdroj: | Chemischer Informationsdienst. 10 |
ISSN: | 0009-2975 |
Popis: | Several kinds of water-soluble dihydropyridine vasodilators were prepared and their vasodilating activities were evaluated. Among them, 2-(N-benzyl-N-methylamino)-ethyl methyl 2, 6-dimethyl-4-(m-nitrophenyl)-1, 4-dihydropyridine-3, 5-dicarboxylate hydrochloride (YC-93) was found to have outstanding activity and bioavailability. Various synthetic routes for this compound were examined. |
Databáze: | OpenAIRE |
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