ChemInform Abstract: SYNTHESIS OF NEW WATER-SOLUBLE DIHYDROPYRIDINE VASODILATORS

Autor:	Ryutaro Kawai, Toichi Takenaka, Fujimoto Masaharu, Tamazawa Kazuharu, Kozo Takahashi, Murakami Masuo, Iwanami Masaru, Tadao Shibanuma
Rok vydání:	1979
Předmět:	chemistry.chemical_compound Water soluble chemistry Hydrochloride Dihydropyridine medicine Organic chemistry Vasodilation General Medicine medicine.drug Bioavailability
Zdroj:	Chemischer Informationsdienst. 10
ISSN:	0009-2975
Popis:	Several kinds of water-soluble dihydropyridine vasodilators were prepared and their vasodilating activities were evaluated. Among them, 2-(N-benzyl-N-methylamino)-ethyl methyl 2, 6-dimethyl-4-(m-nitrophenyl)-1, 4-dihydropyridine-3, 5-dicarboxylate hydrochloride (YC-93) was found to have outstanding activity and bioavailability. Various synthetic routes for this compound were examined.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::61d37ebd6194b5608e3d025a34744333 https://doi.org/10.1002/chin.197944212 Zobrazit plný text záznamu Plný text