Reanalysis of the biotransformation of 4(20),11(12)-taxadiene derivatives

Autor:	Orval A. Mamer, Françoise Sauriol, Di-An Sun, Lolita O. Zamir
Rok vydání:	2001
Předmět:	Terpene chemistry.chemical_compound Taxane Biotransformation Chemistry Stereochemistry Organic Chemistry Taxadiene Organic chemistry General Chemistry Absidia coerulea Catalysis Terpenoid
Zdroj:	Canadian Journal of Chemistry. 79:1381-1393
ISSN:	1480-3291 0008-4042
Popis:	Reanalysis of the biotransformation of 4(20),11(12)-taxadiene derivatives by Absidia coerulea ATCC 10738a unravelled additional unprecedented rearrangement reactions. 5α,7β,9α,10β,13α-pentaacetoxy-4(20),11(12)-taxadiene (1) was converted to 10 new minor taxane derivatives in addition to the previously reported C-1, C-14-hydroxylations and C-15-hydroxylated abeo-taxane. In addition, 2-deacetoxytaxinine J (2) was successfully metabolized with the same fungi.Key words: natural products, terpenes and terpenoids, microorganism, oxygenation, rearrangement.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::61aa9c86934eb88f7721da397d8d4c35 https://doi.org/10.1139/v01-125 Zobrazit plný text záznamu Plný text ve formátu PDF