Response of Ulcerated Necrobiosis Lipoidica to Clofazimine

Autor: Gisela Metzler, Annette Geyer, Frauke Benedix, Anke Strölin, Martin Röcken, Verena Lichte
Rok vydání: 2009
Předmět:
Zdroj: Acta Dermato Venereologica. 89:651-652
ISSN: 0001-5555
Popis: © 2009 The Authors. doi: 10.2340/00015555-0722 Journal Compilation © 2009 Acta Dermato-Venereologica. ISSN 0001-5555 Sir, Necrobiosis lipoidica (NL) is a chronic granulomatous inflammatory disease of the skin of unknown aetiology, which can be associated with diabetes mellitus. NL is characterized by slowly growing initially erythematous plaques that turn into yellow-brown, partly telangiectatic and atrophic scars. Ulcerations occur in approximately 35% of cases. Many therapies have been recommended for this chronic disease; nevertheless, therapeutic success is rare. We report here the successful treatment of ulcerated NL with clofazimine, without noteworthy side-effects.
Databáze: OpenAIRE