The development of a new catalytic process: Bu3SnH-catalyzed reductive cyclization of enals and enones

Autor:	David S. Hays, Gregory C. Fu
Rok vydání:	1999
Předmět:	Chemistry Scientific method Organic Chemistry Drug Discovery Organic chemistry Biochemistry Catalysis
Zdroj:	Tetrahedron. 55:8815-8832
ISSN:	0040-4020
DOI:	10.1016/s0040-4020(99)00446-9
Popis:	By sequencing two known reactions, a new catalytic carbon-carbon bond-forming process, the Bu 3 SnH-catalyzed, PhSiH 3 -mediated reductive cyclization of enals and enones, has been developed. The addition of EtOH to the reactions leads to reproducibly good yields of the cyclized products; a rationale for including this additive is provided.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::61a2ba6dc42bff8bd0917419bdd4579c https://doi.org/10.1016/s0040-4020(99)00446-9 Zobrazit plný text záznamu Full Text from ScienceDirect