Use ofN,N′-Dimethylpropyleneurea (DMPU) as Solvent in the Efficient Preparation of Enantiomerically Pure Secondary Amines

Autor:	Peter Murer, Dieter Seebach, Eusebio Juaristi
Rok vydání:	1993
Předmět:	Solvent chemistry.chemical_compound DMPU Chemistry Organic Chemistry Organic chemistry Alkylation Solvent effects Aliphatic compound Catalysis
Zdroj:	Synthesis. 1993:1243-1246
ISSN:	1437-210X 0039-7881
DOI:	10.1055/s-1993-26035
Popis:	The monoalkylation of (R)- and (S)-1-phenylethylamine proceeds readily with DMPU as the solvent. An efficient procedure was then developed for the high-yield preparation of the chiral secondary amines N-benzyl-, N-isopropyl-, N-(2-biphenylyl)methyl-, N-(diphenyl)methyl-, and N-(2,2-dimethyl)propyl-1-phenylethylamine, in enantiomerically pure form
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::61a26c3e3c557ba9c82af7b1dca2973c https://doi.org/10.1055/s-1993-26035 Zobrazit plný text záznamu