Autor:	Amit Simlandy, Johny Nguyen, Lucas Oxtoby, Quynh Wong, Jason Chen, Keary Engle
Rok vydání:	2022
Popis:	The catalytic enantioselective synthesis of α-chiral alkenes and alkynes represents a powerful strategy for rapid generation of molecular complexity. Herein, we report a transient directing group facilitated site-selective palladium-catalyzed reductive Heck-type hydroalkenylation and hydroalkynylation of alkenylaldehyes using alkenyl and alkynyl bromides, respectively, allowing for construction of a stereocenters at the δ position with respect to the aldehyde.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::619234ffcbcd9586e8f4380b8198860b https://doi.org/10.26434/chemrxiv-2022-h8w0k Zobrazit plný text záznamu