SYNTHESIS, CHARACTERIZATION AND CRYSTAL STRUCTURE OF 3'-[(4-FLUOROPHENYL)CARBONYL]-5'-(HYDROXYMETHYL)-4’-PHENYL SPIRO[INDOLE-3,2'-PYRROLIDIN]-2(1H)-ONE
| Autor: | Sharma, Ratika, Sapnakumari, M., Narayana, B., Sarojini, B. K., Gupta, Vivek K., Kant, Rajni |
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| Jazyk: | angličtina |
| Rok vydání: | 2013 |
| DOI: | 10.17628/ecb.2014.3.183-186 |
| Popis: | The title compound 3'-[(4-fluorophenyl)carbonyl]-5'-(hydroxymethyl)-4’-phenyl spiro[indole-3,2'-pyrrolidin]-2(1H)-one is synthesized by the straightforward multicomponent reaction of 1-(4-fluorophenyl)-3-phenylprop-2-en-1-one, isatin and serine, and is crystallises in monoclinic space group C2/c.The molecule is essentially planar except one of the pyrrolidin ring which adopts normal envelope conformation. The supermoleular assembly is consolidated by ᴨ-ᴨ interactions [centroid- centroid distance= 3.7983(18)]. The crystal structure is stabilized by one C-H…O intra-hydrogen bond, two N-H…O and one O-H…N inter-hydrogen bonds, and these interactions links the molecules into chain extending along the b-axis. European Chemical Bulletin, Vol 3, No 2 (2014): European Chemical Bulletin |
| Databáze: | OpenAIRE |
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