ANALYSIS OF HIGH-RESOLUTION MICROELECTRODE EEG RECORDINGS IN AN ANIMAL MODEL OF SPONTANEOUS LIMBIC SEIZURES

Autor:	Michael D. Furman, Jürgen Kurths, Paul R. Carney, Marco Thiel, Jennifer Simonotto, Udo Schwarz, C. Komalapriya, M. C. Romano, William L. Ditto
Rok vydání:	2009
Předmět:	medicine.diagnostic_test business.industry Applied Mathematics High resolution Hippocampus Electroencephalography Microelectrode Animal model Recurrence quantification analysis Modeling and Simulation Medicine Ictal business Engineering (miscellaneous) Neuroscience Limbic epilepsy
Zdroj:	International Journal of Bifurcation and Chaos. 19:605-617
ISSN:	1793-6551 0218-1274
Popis:	We perform a systematic data analysis on high resolution (0.5–12 kHz) multiarray microelectrode recordings from an animal model of spontaneous limbic epilepsy, to investigate the role of high frequency oscillations and the occurrence of early precursors for seizures. Results of spectral analysis confirm the importance of very high frequency oscillations (even greater than 600 Hz) in normal (healthy) and abnormal (epileptic) hippocampus. Furthermore, we show that the measures of Recurrence Quantification Analysis (RQA) and Recurrence Time Statistics (RTS) are successful in indicating, rather uniquely, the onset of ictal state and the occurrence of some warnings/precursors during the pre-ictal state, in contrast to the linear measures investigated.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::617a76e9bb895ee2653c7aaf8abfdf14 https://doi.org/10.1142/s0218127409023226 Zobrazit plný text záznamu