Bioorganometallic Chemistry: Reactions of Methyltitanocene Cation Complexes with a Singly Deprotected Methyl Glucopyranoside
| Autor: | Jutta Pyplo-Schnieders, Jens Müller, Hartmut Redlich, Birgit Meyer zu Berstenhorst, Gerhard Erker, Julia-Christina Wasilke, Gerald Kehr |
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| Rok vydání: | 2004 |
| Předmět: |
chemistry.chemical_classification
Chemistry Stereochemistry Bioorganometallic chemistry Salt (chemistry) Ionic bonding Medicinal chemistry Inorganic Chemistry Metal chemistry.chemical_compound visual_art Yield (chemistry) visual_art.visual_art_medium Chelation Lewis acids and bases Derivative (chemistry) |
| Zdroj: | European Journal of Inorganic Chemistry. 2005:92-99 |
| ISSN: | 1099-0682 1434-1948 |
| DOI: | 10.1002/ejic.200400387 |
| Popis: | The dimethyltitanocene/B(C6F5)3 system reacts with the 4-unprotected methyl α-D-glucopyranoside derivative 5 (“HO-carb.”) to yield the ionic complex [Cp2Ti(O-carb.)]+[MeB(C6F5)3]− (10a). Spectroscopic studies have led us to believe that 10a is characterized by an internal ether-chelate structure in solution that involves coordination of the 6-OCH2Ph oxygen atom. Treatment of 10a with trimethylphosphane gives the open, non-chelated complex 11a, in which the phosphane coordinates to the metal center. Reaction of the THF-stabilized salt [Cp2TiCH3(THF)]+[BPh4]− (12a) with 5 gave complex 13a, with coordinated THF. Experiments with bis(methylcyclopentadienyl)titanium systems gave analogous results (complexes 10b, 11b and 13b). Zirconocenes react differently. Addition of dimethylzirconocene (14a) or dimethylbis(methylcyclopentadienyl)zirconium (14b) to 5 gave the neutral complexes 15a, 15b and methane. Treatment of 15a (15b) with B(C6F5)3 again resulted in the formation of an ionic chelate complex 16a (16b). A non-chelated complex 18 was formed by treating the THF-stabilized salt [Cp2ZrCH3(THF)]+[BPh4]− (17) with 5. (© Wiley-VCH Verlag GmbH & Co. KGaA, 69451 Weinheim, Germany, 2005) |
| Databáze: | OpenAIRE |
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