Study of Contrast-to-Noise Ratio performance of a Medipix3RX CdTe detector for low dose mammography imaging
| Autor: | S. Procz, Maria L. Pérez-Lara, Luis Orlando Ruiz Mendoza, Gerardo Roque, Carlos Avila |
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| Rok vydání: | 2021 |
| Předmět: |
Physics
Nuclear and High Energy Physics medicine.diagnostic_test 010308 nuclear & particles physics Image quality business.industry Detector 01 natural sciences Dot pitch Cadmium telluride photovoltaics Flat panel detector 030218 nuclear medicine & medical imaging 03 medical and health sciences 0302 clinical medicine Optics Contrast-to-noise ratio 0103 physical sciences medicine Mammography Microcalcification medicine.symptom business Instrumentation |
| Zdroj: | Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 992:165000 |
| ISSN: | 0168-9002 |
| Popis: | This study compares detector performance through measurements of Contrast-to-Noise Ratio (CNR) of images obtained by a standard commercial X-ray mammography setup, using a flat panel detector with a 200 μ m thick amorphous Selenium (a-Se) sensor, and a laboratory setup, using a Medipix3RX detector with a 1 mm thick Cadmium Telluride (CdTe) semiconductor sensor. The laboratory setup corresponds to the geometry and X-ray spectrum of the commercial setup. Dose calibrations are applied to ensure comparability of results between both systems. Detection of microcalcifications in breast tissue is crucial for early medical diagnosis of breast cancer development, and improvements in image quality or reduction in radiation dose significantly benefit the field of mammography imaging. The Medipix3RX CdTe detector has the potential to improve mammography imaging due to a combination of two features: a photon-counting detection scheme that allows for electronic noise rejection, integrated in a small pixel pitch of 55 μ m; and the higher X-ray photon absorption efficiency of CdTe, compared to materials such as Silicon (Si) or Se, in the mammography energy range. The comparison between both systems shows better CdTe detector performance when imaging microcalcification structures with sizes between 240 μ m and 540 μ m. The Medipix3RX CdTe detector produces higher CNR values as compared to the a-Se system for the studied speck sizes, at equivalent doses, with up to 30% for 540 μ m structures. For 240 μ m size specks, the Medipix3RX CdTe detector has more than twice better CNR performance than a-Se, even for half the dose values. Our results motivate further research to exploit the potential of the Medipix3RX CdTe detector for clinical mammography implementations, due to the benefit of simultaneous radiation dose reduction and improved imaging performance. |
| Databáze: | OpenAIRE |
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