Preparative separation of enantiomers using hollow-fiber membrane technology

Autor: William E. Bowen, William H. Pirkle
Rok vydání: 1994
Předmět:
Zdroj: Tetrahedron: Asymmetry. 5:773-776
ISSN: 0957-4166
DOI: 10.1016/s0957-4166(00)86224-2
Popis: Several chromatographically developed chiral selectors show promise for large scale separation of enantiomers using hollow-fiber membrane technology. Chiral selectors derived from N -(1-naphthyl) leucine have been used in a hollow-fiber membrane system (Sepracor) to separate the enantiomers of amino acid derivatives. Enantiomeric purities exceeding 95% have been obtained in a single pass through the system. For data collection, sample sizes were limited to giam quantities of racemate.
Databáze: OpenAIRE