LEUKOCYTE ADHESION DEFECT: A RARE CAUSE OF IMMUNODEFICIENCY

Autor:	Sona Chowdhary, Mohitesh Kumar
Rok vydání:	2014
Předmět:	Pathology medicine.medical_specialty biology business.industry Leukocyte adhesion deficiency-1 Integrin Adhesion medicine.disease Neutrophilia Leukocyte function Immunology medicine biology.protein medicine.symptom business Immunodeficiency circulatory and respiratory physiology
Zdroj:	Indian Journal of Child Health. :153-154
ISSN:	2349-6126 2349-6118
DOI:	10.32677/ijch.2014.v01.i03.014
Popis:	Leukocyte adhesion deficiency 1 (LAD-1) is a rare autosomal recessive disorder of leukocyte function due to integrin deficiency. It is characterized by recurrent bacterial and fungal infections and depressed inflammatory responses despite striking blood neutrophilia. Severe LAD usually presents early in infancy. Here, we report a case who presented late with symptoms of LAD-1 when compared with earlier reported cases and without the usually associated infections. Key words: Autosomal recessive, Integrin, Leukocyte adhesion defect, Neutrophilia
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::613a2f0963e9811f911e8468a94504ed https://doi.org/10.32677/ijch.2014.v01.i03.014 Zobrazit plný text záznamu