Vulval Cancer: When should I Stop Resecting? Identifying the Factors that Predict Recurrence

Autor:	Claire Newton, Vivek Nama, Sarah L. Platt, Pauline J. Humphrey, Joya Pawade
Rok vydání:	2019
Předmět:	medicine.medical_specialty Groin business.industry Context (language use) Disease Logistic regression Lymphovascular Surgery Dissection medicine.anatomical_structure Oncology Pediatrics Perinatology and Child Health medicine Resection margin Stage (cooking) business
Zdroj:	Indian Journal of Medical and Paediatric Oncology. 40:358-364
ISSN:	0975-2129 0971-5851
DOI:	10.4103/ijmpo.ijmpo_138_17
Popis:	Context: Vulval cancer surgery has become more conservative and it is important to understand whether resection margins alone influence recurrence rates or whether other prognostic factors should be considered when planning treatment. Aims: The aim of this study is to define factors that predict vulval cancer recurrence, enabling development of a recurrence prediction model. Settings and Design: This was a Aretrospective descriptive analysis of new vulval squamous cell carcinoma cases in a gynecological oncology center (January 1, 2007 to December 31, 2013). Subjects and Methods: Analysis of tumor characteristics and treatments. Patient outcomes were recorded, identifying recurrences, and subsequent interventions. Statistical Analysis Used: Univariable and multivariable logistic regression tools applied to determine recurrence risk factors. Results: Seventy patients underwent primary vulval surgery. Bilateral groin node dissection was performed in 26/70 (37.1%) cases and unilateral groin node dissection in 9/70 (12.9%) cases. 57/70 (82%) cases had a negative vulval resection margin, with 67%
Databáze:	OpenAIRE
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