Vitamin D Supplementation in Sarcoidosis: A Double-Edged Sword

Autor: Lakshmi Nagendra, Giridhar Belur Hosmane, Bhagavan Kr, Rishikesh Chandran, Shrikrishna Acharya, Adithi Kellarai, Vijith Shetty
Rok vydání: 2021
Předmět:
Zdroj: Journal of Health and Allied Sciences NU. 12:214-216
ISSN: 2582-4953
2582-4287
DOI: 10.1055/s-0041-1736280
Popis: Sarcoidosis is complicated by disordered vitamin D and calcium metabolism, which has important implications on disease activity and bone health. Although the majority of the patients with sarcoidosis are typically deficient in 25-hydroxyvitamin D, repletion of vitamin D is controversial in light of the hypercalcemia risk. Presently, there are no clear guidelines regarding vitamin D supplementation as a part of osteoporosis prevention in patients with vitamin D deficiency and sarcoidosis. We report a patient with sarcoidosis who presented with severe hypercalcemia following vitamin D supplementation and review the debated role of vitamin D supplementation in vitamin D-deficient sarcoid patients.
Databáze: OpenAIRE