Surgical treatment of penile cancer.A follow-up report

Autor: Robert H. Moore, Zew Wajsman, Gerald P. Murphy, Claude Merrin
Rok vydání: 1977
Předmět:
Zdroj: Cancer. 40:1697-1701
ISSN: 1097-0142
0008-543X
DOI: 10.1002/1097-0142(197710)40:4<1697::aid-cncr2820400445>3.0.co;2-t
Popis: One hundred and fifteen patients with penile cancer were treated at Roswell Park Memorial Institute from 1952 through 1975. A full follow-up is reported and factors involving the prognosis are analyzed. Although the clinical error of staging was near 30%, the lymphography results suggest that this study may result in added improvement in preoperative staging. Early diagnosis, adequate surgical resection, and lymph node dissection will improve the survival significantly. When dealing with an individual patient the prognosis is poor when any one or more of the following factors are present: the lesion involves the shaft; there is a positive margin at the surgical resection; total penectomy is necessary to obtain tumor-free margin; lymphography is positive for tumor involvement of lymph nodes; lymph node dissection has not been performed; positive lymph nodes are found on surgical exploration. The good prognostic factors include: a lesion confined to the glans and partial penectomy is sufficient to obtain a tumor-free margin of resection; no clinical evidence (including lymphography) of lymph node involvement; performance of lymph node dissection. The histological grading of the tumor should not influence the clinical decision for treatment in our opinion at this time, based on our current results. Further prospective studies of different factors involved in etiology, diagnosis, and treatment of penile cancer are suggested.
Databáze: OpenAIRE
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