Fractional Factorial Design Approach for Optimizing Analytical Methods

Autor:	Philip J Oles
Rok vydání:	1993
Předmět:	Pharmacology Mathematical optimization Materials science Environmental Chemistry Fractional factorial design Factorial experiment Agronomy and Crop Science Analysis method Food Science Analytical Chemistry
Zdroj:	Journal of AOAC INTERNATIONAL. 76:615-620
ISSN:	1944-7922 1060-3271
DOI:	10.1093/jaoac/76.3.615
Popis:	Experimental designs based on procedures of Taguchi are described for optimizing analytical methods. Methods were efficiently developed, with improvements in precision and accuracy, for the determination of cholesterol in foods, magnesium in feed premix, and moisture in mayonnaise. Significant factors and interactions were identified by using 2-level designs, analysis of variance techniques, and commercially available computer software. The designs were prepared by using Taguchi linear diagrams. The methods developed as a result of these experiments have proven to be rugged and reliable.
Databáze:	OpenAIRE
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