Interphase chromatin of lymphocytes in patients with disturbed sex differentiation
| Autor: | A. B. Okulov, Z. L. Lemeneva, K. N. Fedorova, I. É. Yudina |
|---|---|
| Rok vydání: | 1984 |
| Předmět: |
Thymus extract
Thermal denaturation endocrine system medicine.medical_specialty animal structures Cell division General Medicine Cell movement Biology Turner's syndrome Molecular biology General Biochemistry Genetics and Molecular Biology Endocrinology Internal medicine embryonic structures medicine MORRIS SYNDROME hormones hormone substitutes and hormone antagonists Thymocyte migration |
| Zdroj: | Bulletin of Experimental Biology and Medicine. 97:101-103 |
| ISSN: | 1573-8221 0007-4888 |
| DOI: | 10.1007/bf00830257 |
| Popis: | Morphometry was used to study the effect of T-activin on the morphology of the thymus of (CBA X C57BL) F1 mice given 10, 15 and 20 injections of T-activin (1.0 micrograms i.p.). T-activin did not cause any pathological alterations in the thymus. Ten injections of T-activin activated the proliferation and migration of thymocytes from the thymus. Fifteen injections of T-activin eventuated in an increased surge of thymocyte migration from the thymus, whereas 20 injections gave rise to a new surge of proliferation and preparation or beginning of thymocyte migration from the thymus. It is concluded that prolonged injection of T-activin does not disturb the fluctuation pattern of thymus functioning but activates the transformation and migration of thymocytes. |
| Databáze: | OpenAIRE |
| Externí odkaz: |
|
Full text from SpringerLink