Osteolytic Lesions in Secondary Syphilis

Autor:	Hugh D. Bennett, Harry A. Kiesel, Ronald N. Shore
Rok vydání:	1977
Předmět:	Pathology medicine.medical_specialty Necrosis medicine.diagnostic_test business.industry Plasma cell medicine.disease Vascularity medicine.anatomical_structure Biopsy Internal Medicine medicine Syphilis Histopathology medicine.symptom Fibula business Bone pain
Zdroj:	Archives of Internal Medicine. 137:1465
ISSN:	0003-9926 1465-1467
DOI:	10.1001/archinte.1977.03630220095023
Popis:	A 37-year-old man was admitted with bone pain, night sweats, and skin lesions typical of secondary syphilis. His VDRL and FTA-ABS tests were reactive. Roentgenograms of the tibiae, fibulae, radii, and ulnae showed osteolytic lesions. A tibial biopsy examination showed bone necrosis, prominent vascularity, swollen endothelial cells, an intense plasma cell infiltrate, and numerous spirochetes. All manifestations responded to penicillin therapy. There have been few reports of osteolytic lesions in secondary syphilis. This is the first known case in which such involvement was unequivocally proven by histopathology with the demonstration of spirochetes. (Arch Intern Med137:1465-1467, 1977)
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::60e5deb55aeba8ce4a2f36812b3cb747 https://doi.org/10.1001/archinte.1977.03630220095023 Zobrazit plný text záznamu