Autor:	A. G. Zavozin, N. E. Kravchenko, E. E. Rumyantseva, S. I. Zav'yalov, G. I. Ezhova, Olga V. Dorofeeva, L. B. Kulikova
Rok vydání:	2001
Předmět:	Pharmacology chemistry.chemical_compound Chemistry Sulfanyl Drug Discovery 2-aminothiazole Pharmacology toxicology Urea Levulinic acid Halogenation Organic chemistry Biological activity Chloroacetyl chloride
Zdroj:	Pharmaceutical Chemistry Journal. 35:96-98
ISSN:	0091-150X
DOI:	10.1023/a:1010477022450
Popis:	The optimum amount of urea for the selective bromination of ketones in DMF has been established. The obtained α-bromoketones have been used for the synthesis of 2-aminothiazoles in situ. A series of compounds with potential biological activity has been synthesized proceeding from chloroacetyl derivatives of 2-aminothiazoles.
Databáze:	OpenAIRE
Externí odkaz:	https://explore.openaire.eu/search/publication?articleId=doi_________::60e361b568d3789a66fb5ef92cd710b3 https://doi.org/10.1023/a:1010477022450 Zobrazit plný text záznamu Full text from SpringerLink